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- W2384017112 abstract "Basal autophagy plays an important role in cellular homeostasis that is via the degradation of aggregate-prone protein,long-lived protein and damaged organelles.The processes of autophagy is controlled by complex signaling pathways.Cytoplasmic components are enclosed by double-membrane autophagosomes,which subsequently fuse with lysosomes for degradation.Autophagy dysfunction contributes to the pathology of various neurodegenerative disorders,such as Alzheimer's disease,Parkinson disease,Huntington disease.These diseases have abnormal protein accumulation.Neurons cannot get rid of their wastes through cell division.Autophagy maintenance of neuronal function is particularly important." @default.
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- W2384017112 date "2011-01-01" @default.
- W2384017112 modified "2023-09-29" @default.
- W2384017112 title "Autophagy and neurodegeneration" @default.
- W2384017112 hasPublicationYear "2011" @default.
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