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- W2384017839 abstract "Aim:To explore the genotoxicity of organic extract of vehicle exhaust on HepG2 cells in vitro.Methods:Cytokinesis-block micronucleus assay and comet assay were used to evaluate the genotoxicity of organic extract of vehicle exhaust(2.5,5.0 and 10.0 mg/L)on HepG2 cells.The solvent control group and positive control group were used as control.Results:There were significant differences in frequency of cytokinesis-block micronucleus and Olive tail moment among five groups(F=18.608 and 9.525,P0.001).A significant increased frequency of cytokinesis-block micronucleus was observed in both 5.0 and 10.0 mg/L dose group compared with the solvent control group(P0.05).A significant increased Olive tail moment was observed in three dose groups compared with the solvent control group(P0.05).Conclusion:The organic extract of vehicle exhaust has a distinct genotoxicity on HepG2 cells in vitro." @default.
- W2384017839 created "2016-06-24" @default.
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- W2384017839 date "2011-01-01" @default.
- W2384017839 modified "2023-09-22" @default.
- W2384017839 title "Genotoxicity effects of organic extract of vehicle exhaust on HepG2 cells in vitro" @default.
- W2384017839 hasPublicationYear "2011" @default.
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