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- W2384019230 abstract "Objective: To study if there is a relationship between cell adhesion molecule (ICAM), endothelial cell growth factor (EFGF), angiogenesis and gallbladder lesions. Methods: Surgical specimens of 10 cases of chronic cholangitis (CC), 13 of gallbladder dysplasia (GD) and 20 of adenocarcinoma of gallbladder (AG) were morphologically and immunohistochemically investigated for CD 34 , factor VIII, ICAM and EFGF. The microvascular density(MVD) was determined and calculated. Results: A progressively increase of MVD from CC to GD and to AG was noted which was statistic significant difference between CC and AG(P0 05). The expression of ICAM in the 3 groups was strongly parallel to that of EFGF. Both the expression of ICAM and EFGF was the same as MVD and demonstrated a highly statistic significant differences between CC and GD, CC and AG (P0 01). No association, however, occurred of MVD, also of ICAM and VEGF with stage, stadium and invasion of the tumor. Conclusions: Some mechanisms may exist between ICAM, VEGF and angiogenesis, which may play an important role in the oncogenesis of gallblladder lesions. The determination of ICAM, BEGF, and MVD may be a supplementary for differentiation diagnosis of CC, GD and AG." @default.
- W2384019230 created "2016-06-24" @default.
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- W2384019230 date "2002-01-01" @default.
- W2384019230 modified "2023-09-25" @default.
- W2384019230 title "The Relationship Between Cell Adhesion Molecule, Endothelial Cell Growth Factor, Anfiogenesis and Gallbladder Lesions" @default.
- W2384019230 hasPublicationYear "2002" @default.
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