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- W2384021109 abstract "Objective To observe the effect of Qiangji Jianli Yin(QJY) on hypothalamic-pituitary-gonad axis of rats with kidney-yang deficiency syndrome.Methods SD rats were randomized into normal group,model group and QJY groups(treated with QJY at the doses of 7.8,15.6 and 23.4 g·kg-1·d-1 respectively),and Yougui Pill group(at the dose of 5.8 g·kg-1·d-1).Rat models of kidney-yang deficiency syndrome were induced by intramuscular injection of hydrocortisone 25 mg·kg-1·d-1.The outer appearance and activity of daily life of rats were observed,hypothalamus index and testis index were calculated,histological feature of testes was examined,and the serum levels of testosterone(T) and estrogen(E2) were measured by radioimmunoassay(RIA).Results In QJY groups,the hypothalamus index was decreased,serum T level were increased,and E2/T ratio was reduced(P0.01 compared with the model group).The results of histological examination showed that the size of the spermatid in convoluted seminiferous tubule of QJY group was larger than that in the model group,and nuclear chromatin in spermatogonia(PL) and chromosome in primary spermatocytes were presented obviously in QJY group.Conclusion The preventive and therapeutic mechanism of QJY for rats with kidney-yang deficiency syndrome is probably related with the regulation of the hypothalamic-pituitary-gonad axis." @default.
- W2384021109 created "2016-06-24" @default.
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- W2384021109 date "2008-01-01" @default.
- W2384021109 modified "2023-09-23" @default.
- W2384021109 title "Experimental Study on Effect of Qiangji Jianli Yin on Hypothalamic-pituitary-gonad Axis of Rats with Kidney-yang Deficiency Syndrome" @default.
- W2384021109 hasPublicationYear "2008" @default.
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