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- W2384026128 abstract "Objective To analyze the relationship of plasma lipid and adiponectin levels and the incidence of insulin resistance and fatty liver in simple obese children. Methods Fifty-six simple obese children were selected as fatty group, while 60 normal children were selected as control group. The height, waistline, hipline, and body weight were record, and levels of plasma lipid, adiponectin and insulin as well as liver function were detected by ELISA and immunoturbidimetry. Ultrasonography was used to exam the incidence of fatty liver and nonalcoholic fatty liver disease. Results There were obvious differences in body mass index(BMI), waist circumference(WC) and waist-hip(WHR) between the two groups. In fatty group, 43 children were revealed dyslipidmias. There were significant differences in serum FINS, TG, LDL-C, adiponectin and HOMA-IR between the two groups(P0.05). By Pearson correlation analysis, negative correlation was found between adiponectin level and body mass index, TG, LDL-C, FINS,HOMA-IR. In fatty group, there were 13 children with fatty liver, 6 children with nonalcoholic fatty liver disease(NAFLD), and 20 children with liver enlargement. However, in control group, there were only 6 children with liver enlargement. There were significant differences in incidence of fatty liver and NAFLD between the two groups(P0.05).Conclusion The plasma adiponectin levels in simple obese children were lower than those in normal children, which showed negative relationship with TG and HOMA-IR. The incidences of fatty liver, abnormal liver function and NAFLD in simple obese children were higher than those in normal children." @default.
- W2384026128 created "2016-06-24" @default.
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- W2384026128 date "2014-01-01" @default.
- W2384026128 modified "2023-09-27" @default.
- W2384026128 title "Relationship of plasma lipid and adiponectin levels and the incidence of insulin resistance and fatty liver in simple obese children" @default.
- W2384026128 hasPublicationYear "2014" @default.
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