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- W2384027947 abstract "Objective To investigate the multidrug resistance(MDR) of non-small cell lung cancer(NSCLC) and the expression of mdrl gene.Methods 91 cases of NSCLC were tested with MTT assay to evaluate their chemoresistance.The expression of mdrl gene was examined with immunohistochemical assay.Results The percentage of drug resistance of cyclophamide,adriamycin and cisplatin+fluorouracil were(58.2%)、56.0% and 46.2%.The expression percentage of mdrl gene was 58.2%.There is not significant difference in the expression of mdrl between human adeoncarcinoma and sequamous cell carcinoma(P(0.05)).The correlation between the positive expression of mdrl gene and the degrees of chemoresistance to the three kinds of agents was significantly(P0.05).Conclusion There is something between MDR and mdrl gene in NSCLC." @default.
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- W2384027947 date "2006-01-01" @default.
- W2384027947 modified "2023-09-26" @default.
- W2384027947 title "The effection of mdrl in mechanism of drug resistance of non-small cell lung cancer" @default.
- W2384027947 hasPublicationYear "2006" @default.
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