Matches in SemOpenAlex for { <https://semopenalex.org/work/W2384037215> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2384037215 abstract "Objective:To determine the effect of IL-12 on the cellular immune response of PBMC from patients with chronic hepatitis B virus infection, and provide basic scientific information for clinic therapy of this disease.Methods:PBMCS were prepared from peripheral blood of individuals with chronic HBV infection and cultured in the presence or absence of HBsAg and HBcAg with or without IL-12.The level of IFN-γin culture supernatants, the frequency of IFN-γ-producing cells, and the subpopulation of IFN-γ-producing cells were detected by either ELISA,ELISPOT or FACS.Results:Less than 30% patients and very low level of IFN-γ were observed when PBMCs were stimulated with HBsAg or HBcAg alone. Addition of IL-12 to the cultures resulted in significant increase in IFN-γproduction and IFN-γ-producing cells. In addition, IL-12 induced expression of IFN-γ not only by CD8~+T cells, but also by non-T cell populations.Conclusion:IL-12 can promote the cellular immune response to the chronic hepatitis B virus by the enhancement of IFN-γproduction." @default.
- W2384037215 created "2016-06-24" @default.
- W2384037215 creator A5073806292 @default.
- W2384037215 date "2006-01-01" @default.
- W2384037215 modified "2023-09-25" @default.
- W2384037215 title "IL-12 promotes the cellular immunity of PBMC from patients with chronic hepatitis B virus infection in vitro" @default.
- W2384037215 hasPublicationYear "2006" @default.
- W2384037215 type Work @default.
- W2384037215 sameAs 2384037215 @default.
- W2384037215 citedByCount "0" @default.
- W2384037215 crossrefType "journal-article" @default.
- W2384037215 hasAuthorship W2384037215A5073806292 @default.
- W2384037215 hasConcept C137061746 @default.
- W2384037215 hasConcept C159047783 @default.
- W2384037215 hasConcept C167672396 @default.
- W2384037215 hasConcept C202751555 @default.
- W2384037215 hasConcept C203014093 @default.
- W2384037215 hasConcept C2522874641 @default.
- W2384037215 hasConcept C2776178377 @default.
- W2384037215 hasConcept C2777410769 @default.
- W2384037215 hasConcept C2779053233 @default.
- W2384037215 hasConcept C2779729466 @default.
- W2384037215 hasConcept C2780593183 @default.
- W2384037215 hasConcept C3017875465 @default.
- W2384037215 hasConcept C55493867 @default.
- W2384037215 hasConcept C71924100 @default.
- W2384037215 hasConcept C86803240 @default.
- W2384037215 hasConcept C8891405 @default.
- W2384037215 hasConceptScore W2384037215C137061746 @default.
- W2384037215 hasConceptScore W2384037215C159047783 @default.
- W2384037215 hasConceptScore W2384037215C167672396 @default.
- W2384037215 hasConceptScore W2384037215C202751555 @default.
- W2384037215 hasConceptScore W2384037215C203014093 @default.
- W2384037215 hasConceptScore W2384037215C2522874641 @default.
- W2384037215 hasConceptScore W2384037215C2776178377 @default.
- W2384037215 hasConceptScore W2384037215C2777410769 @default.
- W2384037215 hasConceptScore W2384037215C2779053233 @default.
- W2384037215 hasConceptScore W2384037215C2779729466 @default.
- W2384037215 hasConceptScore W2384037215C2780593183 @default.
- W2384037215 hasConceptScore W2384037215C3017875465 @default.
- W2384037215 hasConceptScore W2384037215C55493867 @default.
- W2384037215 hasConceptScore W2384037215C71924100 @default.
- W2384037215 hasConceptScore W2384037215C86803240 @default.
- W2384037215 hasConceptScore W2384037215C8891405 @default.
- W2384037215 hasLocation W23840372151 @default.
- W2384037215 hasOpenAccess W2384037215 @default.
- W2384037215 hasPrimaryLocation W23840372151 @default.
- W2384037215 hasRelatedWork W172377606 @default.
- W2384037215 hasRelatedWork W1967127041 @default.
- W2384037215 hasRelatedWork W1982333769 @default.
- W2384037215 hasRelatedWork W2000347349 @default.
- W2384037215 hasRelatedWork W2023732177 @default.
- W2384037215 hasRelatedWork W2044217736 @default.
- W2384037215 hasRelatedWork W2050144901 @default.
- W2384037215 hasRelatedWork W2076191699 @default.
- W2384037215 hasRelatedWork W2076454038 @default.
- W2384037215 hasRelatedWork W2077458106 @default.
- W2384037215 hasRelatedWork W2124517786 @default.
- W2384037215 hasRelatedWork W2169784691 @default.
- W2384037215 hasRelatedWork W2351041544 @default.
- W2384037215 hasRelatedWork W2412143256 @default.
- W2384037215 hasRelatedWork W2465367208 @default.
- W2384037215 hasRelatedWork W2901072730 @default.
- W2384037215 hasRelatedWork W3119853773 @default.
- W2384037215 hasRelatedWork W3122511660 @default.
- W2384037215 hasRelatedWork W2578000856 @default.
- W2384037215 hasRelatedWork W2585043636 @default.
- W2384037215 isParatext "false" @default.
- W2384037215 isRetracted "false" @default.
- W2384037215 magId "2384037215" @default.
- W2384037215 workType "article" @default.