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- W2384077401 abstract "Objective:To study the relationship between degree of HBV infection and intrauterine infection in pregnant women and determine the value of quantitative detection of HBeAg in diagnosis of intrauterine infection.Methods:HBeAg was quantitatively detected in blood samples from 69 pregnant women with HBV infection and their neonate's umbilical cord by ECL2010 electrochemical luminescent analyzer. Meanwhile, HBsAg, HBeAg, HbeAb and HBcAb were detected with ELISA and HBV DNA determined with PCR. All infants were followed up for 1 year.Results:Of the 69 women, 32 exhibited double positivity of HBsAg and HbeAg. In these 32 women, the level of HBeAg 1 U/ml, HBVDNA 105 copy/ml or 105 copy/ml and the rate of intrauterine infection was 62.5%.In other 37 HbeAg-negative women, the level of HBeAg1 U/ml and the rate of intrauterine infection was 13.5%.The high-risk factors for intrauterine factors were the level of HBeAg1 U/ml, double positivity of HBsAg and HBeAg and high concentration of HBV DNA.Conclusion:Quantitative detection of HBeAg is a highly sensitive, rapid, simple and reliable method for diagnosis of intrauterine infection." @default.
- W2384077401 created "2016-06-24" @default.
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- W2384077401 date "2007-01-01" @default.
- W2384077401 modified "2023-09-25" @default.
- W2384077401 title "Study on HBV infection and intrauterine infection in pregnant women" @default.
- W2384077401 hasPublicationYear "2007" @default.
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