Matches in SemOpenAlex for { <https://semopenalex.org/work/W2384100809> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2384100809 abstract "Objective To investigate the effects of postprocessing of different dosages of vitamin C on renal ischemia-reperfusion injury and the relevant mechanisms of NF-κB p65 in rats.Methods Thirty adult male SD rats were divided randomly into groups Sham,renal ischemia-reperfusion group (RIR),postprocessing of low-dosage Vitamin C (LVcPO),middle-dosage (MVcPO) and high-dosage (HVcPO),6 in each.Serum was collected to detect blood urea nitrogen (BUN) and creatinine (Cr) at hours 2 after reperfusion,and renal tissues were taken to perform homogenate to determine the levels of superoxide dismutase (SOD) activities,malondialdehyde (MDA) and NO.The NF-κB p65 levels in renal tissue were evaluated by immunohistochemical method.Results The levels of BUN,Cr,renal tissue MDA,NO increased (P0.01)but SOD decreased in group RIR(P0.01)as compared with group Sham;those of groups LVcPO,MVcPO,HVcPO decreased(P0.05),but SOD increased(P0.05),when compared with group RIR.NF-κB p65 of group RIR had remarkable positive expression in renal tubular epithelial cells,with a large number of brown-yelllow granules distributing in a diffusing state.Positive cells were more in groups LVcPO,MVcPO,HVcPO than in group Sham,but fewer than in group RIR,the fewest in group HVcPO.Conclusion NF-κB p65 expression and changes of NO level in renal tisssues are closely related to ischemia-reperfusion-induced renal tissue damage.Postprocessing of different dosages of vitamin C inhibits NF-κB p65 expression and reduces NO level,thus to protect effectively renal tissues.It has been found that postprocessing of high-dosage vitamin C can effect more remarkably." @default.
- W2384100809 created "2016-06-24" @default.
- W2384100809 creator A5027346258 @default.
- W2384100809 date "2010-01-01" @default.
- W2384100809 modified "2023-09-22" @default.
- W2384100809 title "Effects of Postprocessing of Different Dosages of Vitamin C on Renal Ischemia-reperfusion Injury in Rats" @default.
- W2384100809 hasPublicationYear "2010" @default.
- W2384100809 type Work @default.
- W2384100809 sameAs 2384100809 @default.
- W2384100809 citedByCount "0" @default.
- W2384100809 crossrefType "journal-article" @default.
- W2384100809 hasAuthorship W2384100809A5027346258 @default.
- W2384100809 hasConcept C126322002 @default.
- W2384100809 hasConcept C134018914 @default.
- W2384100809 hasConcept C162156334 @default.
- W2384100809 hasConcept C204232928 @default.
- W2384100809 hasConcept C2775838275 @default.
- W2384100809 hasConcept C2776151105 @default.
- W2384100809 hasConcept C2777785397 @default.
- W2384100809 hasConcept C2778176769 @default.
- W2384100809 hasConcept C2778401633 @default.
- W2384100809 hasConcept C2780022331 @default.
- W2384100809 hasConcept C2780091579 @default.
- W2384100809 hasConcept C2780114680 @default.
- W2384100809 hasConcept C2780306776 @default.
- W2384100809 hasConcept C2780721119 @default.
- W2384100809 hasConcept C541997718 @default.
- W2384100809 hasConcept C71924100 @default.
- W2384100809 hasConcept C98274493 @default.
- W2384100809 hasConceptScore W2384100809C126322002 @default.
- W2384100809 hasConceptScore W2384100809C134018914 @default.
- W2384100809 hasConceptScore W2384100809C162156334 @default.
- W2384100809 hasConceptScore W2384100809C204232928 @default.
- W2384100809 hasConceptScore W2384100809C2775838275 @default.
- W2384100809 hasConceptScore W2384100809C2776151105 @default.
- W2384100809 hasConceptScore W2384100809C2777785397 @default.
- W2384100809 hasConceptScore W2384100809C2778176769 @default.
- W2384100809 hasConceptScore W2384100809C2778401633 @default.
- W2384100809 hasConceptScore W2384100809C2780022331 @default.
- W2384100809 hasConceptScore W2384100809C2780091579 @default.
- W2384100809 hasConceptScore W2384100809C2780114680 @default.
- W2384100809 hasConceptScore W2384100809C2780306776 @default.
- W2384100809 hasConceptScore W2384100809C2780721119 @default.
- W2384100809 hasConceptScore W2384100809C541997718 @default.
- W2384100809 hasConceptScore W2384100809C71924100 @default.
- W2384100809 hasConceptScore W2384100809C98274493 @default.
- W2384100809 hasLocation W23841008091 @default.
- W2384100809 hasOpenAccess W2384100809 @default.
- W2384100809 hasPrimaryLocation W23841008091 @default.
- W2384100809 hasRelatedWork W1056603737 @default.
- W2384100809 hasRelatedWork W2348628560 @default.
- W2384100809 hasRelatedWork W2349335352 @default.
- W2384100809 hasRelatedWork W2352648156 @default.
- W2384100809 hasRelatedWork W2357959636 @default.
- W2384100809 hasRelatedWork W2358124521 @default.
- W2384100809 hasRelatedWork W2358214494 @default.
- W2384100809 hasRelatedWork W2365102824 @default.
- W2384100809 hasRelatedWork W2366370844 @default.
- W2384100809 hasRelatedWork W2369136874 @default.
- W2384100809 hasRelatedWork W2369633584 @default.
- W2384100809 hasRelatedWork W2371341332 @default.
- W2384100809 hasRelatedWork W2375970768 @default.
- W2384100809 hasRelatedWork W2384401916 @default.
- W2384100809 hasRelatedWork W2390847726 @default.
- W2384100809 hasRelatedWork W2391339976 @default.
- W2384100809 hasRelatedWork W2391347467 @default.
- W2384100809 hasRelatedWork W2897621131 @default.
- W2384100809 hasRelatedWork W3028652581 @default.
- W2384100809 hasRelatedWork W3028791868 @default.
- W2384100809 isParatext "false" @default.
- W2384100809 isRetracted "false" @default.
- W2384100809 magId "2384100809" @default.
- W2384100809 workType "article" @default.