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- W2384102280 abstract "Objective To investigate the effect of ABO-incompatible myeloablative allogeneic hematopoietic stem cell transplantation(allo-HSCT) on hematopoietic engraftment.Methods The clinical data of 21patients who received ABO-incompatible allo-HSCT in the First Affiliate Hospital of Wenzhou Medical College from April 2007 to December 2011 were analyzed.Twenty patients matched who received ABO-compatible allo-HSCT in the same period served as controls.Blood routine examination was dynamically observed and analyzed between the 2 groups.Results The recovery of erythrocytic series reconstitution was prolonged to 20 d in ABO-incompatible patients as compared to 10.5 d in ABO-compatible patients(P 0.05).No difference in platelet and the neutrophil reconstitution was noted between the ABO-compatible and ABO-incompatible patients(P 0.05).Time of red blood cells engraftment was not different among major,minor,and bidirectional ABOincompatible groups(P 0.05).Cox proportional hazard model analysis demonstrated that number of CD34 + cells were correlated with erythrocytic series in ABO-incompatible patients(P 0.05).Conclusions Myeloablative allo-HSCT is safe in ABO-incompatible patients if there is any indication.The number of CD34 + cells are correlated with erythrocytic series." @default.
- W2384102280 created "2016-06-24" @default.
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- W2384102280 date "2012-01-01" @default.
- W2384102280 modified "2023-09-24" @default.
- W2384102280 title "Effect of ABO-incompatible myeloablative allogeneic hematopoietic stem cell transplantation on hematopoietic engraftment" @default.
- W2384102280 hasPublicationYear "2012" @default.
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