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- W2384112899 abstract "The amount of viable biomass is an important physiological parameter,which is correlated with the cell growth,metabolism and productivity during the rifamycins SV fermentation process. The measurement of viable biomass was studied employing on-line Biomass Monitor. It was able to utilize the dielectric properties of cells,and the capacitance measurement was correlated well with the viable biomass concentration excluding the interference of solid materials. At the same time, there was close connections among the capacitance measurement,OUR,CER and mycelial morphology. The diauxic growth phenomenon in the former fermentation was detected using capacitance detection,and the slow-release nitrogen source soyben powder instead of the original expensive fast-release nitrogen source of peptone was used for rifamycins SV fermentation,successfully eliminated the diauxic growth caused by nitrogen source using the conversion of stagnation,the physiological parameters of OUR and CER reached and maintained at 14. 8 and 15. 3 mmol /L /h at early growth phase,significantly higher than that under peptone conditions for only 8. 6 and 11. 3 mmol /L /h,which promote the continued higher rifamycin SV biosynthesis,the fermentation titer reached to 5969 + 19 U /ml,which was18. 7% higher than that of control(5030 + 17 U /ml)." @default.
- W2384112899 created "2016-06-24" @default.
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- W2384112899 date "2014-01-01" @default.
- W2384112899 modified "2023-09-25" @default.
- W2384112899 title "Studies on the Measurement of Viable Biomass in the Optimization of Rifamycins SV Fermentation Process" @default.
- W2384112899 hasPublicationYear "2014" @default.
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