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- W2384131588 abstract "Objective: To investigate whether peripheral blood levels of matrix metalloproteases-9 (MMP-9) and C-reactive protein(CRP) were affected in patients with coronary artery disease (CAD).Method:Using ELISA and scatter rate nephelometry, plasma MMP-9 and CRP were measured in 22 patients with acute myocardial infarction(AMI),17 with unstable angina(UA), 17 with stable angina (SA) and 17 control normal subjects.Result:①The serum levels of MMP-9 in AMI?UA and SA group were significantly higher than the control groups(P0.01,P0.05). ②The serum level of CRP was higher in AMI and UA group than the control group(P0.01), but there were no different significance of CRP's level between SA and control groups. ③The serum levels of MMP-9 in AMI?UA group were markedly higher than SA groups(P0.01). ④the serum level of MMP-9 and CRP were significantly different between UA group than AMI group(P0.01). ⑤There was no obvious correlation between MMP-9 and CRP in ACS group(P=0.3780.05).Conclusion:The increased serumal levels of MMP-9 and CRP in patients with coronary artery disease may predict the unstable conditions of plaques.The fact that there was no correlation between MMP-9 and CRP suggests that the different aspects which predict the unstability of plaques .It may be more beneficial to predicting the stability of atherosclerosis plaques and forecasting acute cardiovascular risk by combination detection of serumal levels of MMP-9 and CRP." @default.
- W2384131588 created "2016-06-24" @default.
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- W2384131588 date "2006-01-01" @default.
- W2384131588 modified "2023-09-23" @default.
- W2384131588 title "Changes and implication of peripheral blood levels of matrix metalloproteases-9 and C-reactive protein in patients with coronary artery disease" @default.
- W2384131588 hasPublicationYear "2006" @default.
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