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- W2384148503 abstract "Objective: To study the changes in different time of Schwann cell in transected sciatic nerve distal stump. Methods: The sciatic nerves were cut at the middle level. Schwann cells (SCs) were obtained from the distal stumps of transected sciatic nerves which had been denervated for 1, 2 weeks and 1 month. The light microscope and loser scanning confocal microscope were used to observe morphological changes. MTT assay was conducted to detect the vitality of SCs. Flow cytometer was used to determine the changes in cell cycle. Results: Some morphological changes were observed especially in the group which had been denerved for 1 month. Besides, there was a progressive decrease in vitality and proliferation rate of SCs with increasing time of denervation. Conclusion: In trauma nerve, there were changes in morphology, vitality and proliferation rate. The longer the time of denervation was, the lower the vitality and proliferation ability of SCs was, however, the SCs do not stop proliferating though they have been denerved for 1 month." @default.
- W2384148503 created "2016-06-24" @default.
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- W2384148503 date "2006-01-01" @default.
- W2384148503 modified "2023-09-22" @default.
- W2384148503 title "Changes of Schwann cells in transected sciatic nerve distal stumps of adult rats in vitro" @default.
- W2384148503 hasPublicationYear "2006" @default.
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