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- W2384157265 abstract "Objective:To investigate the effect of interferon-γ(IFN-γ) on the expression of proliferating cell nuclear antigen((PCNA)) in rabbit lens epithelial cells(LECs).Methods:Extracapsular lens extration models were made in rabbits,and IFN-γ was irrigated into the capsular bag during operation.The rabbits were divided into 3 groups.Group A,the control group,was irrigated only with BSS during operation.Group B and group C,the treatment groups,were irrigated with IFN-γ,of concentration 10~3IU/ml,10~4IU/ml respectively.Three months later,the expression of PCNA in LECs were identified with immunohistochemical staining and automatic image analysis technology.Results:The expression of PCNA in IFN-γ group was lower than that of control group (P0.05).Conclusions:The experiment shows that IFN-γ can inhibit the expression of the PCNA in rabbit LECs,and the inhibition of IFN-γ on PCNA is concentration-dependent." @default.
- W2384157265 created "2016-06-24" @default.
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- W2384157265 date "2004-01-01" @default.
- W2384157265 modified "2023-09-24" @default.
- W2384157265 title "Effects of interferon-γ on the expression of proliferating cell nuclear antigen in lens epithelial cells" @default.
- W2384157265 hasPublicationYear "2004" @default.
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