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- W2384164708 abstract "In order to probe the effects of the immunotherapy for swine cysticercosis with the genetic engineering vaccine,the pigs infected experimentally or naturally with cysticercosis were treated with the vaccine. 10 pigs which were infected experimentally cysticercosis were randomly divided into three groups: l)four pigs,each was injected the genetic engineering vaccine against swine cysticercosis after one month of infection for three times at interval of fifteen days; 2)four pigs,each was injected the vaccine as above after two months of infection; 3)two pigs,each was injected nothing.The sera CA of all the infected pigs were positive,which were detected by sandwich ELISA,and their OD values were between 0.9 and 1.42 after one month of infection.In the first group,the OD values began to decrease in one month of the first injection of the vaccine,and one of the CAs was negative in 2.0,2.5and 3.5 months,respectively,no cysticerci was found.In the second group,cysticerci was found in the detected muscles of all the four pigs:masseter,septonles,psoas,vastus medialis and scapulae externus.The number of cysticerci hosted in the detected pork was 3 to 7 per 40 cm 2.Their bile hatching rates were 15.4%.In the third group,the cysticerci were detected in the two pigs,the number of cysticerci hosted in the detected pork was 6 to 9 per 40 cm 2,their bile hatching rates were 90.4%.By epidemic investigation detecting the sera's CA,we confirmed that 25 pigs were infected naturally with cysticercosis.They were divided into three groups as their OD values and were injected with the genetic engineering vaccine as above: 1)7 pigs,their OD values between 0.68 and 0.90; 2)8 pigs,their OD values between 0.91 and 1.10; 3)10 pigs,their OD values between 1.11 and 1.54.Six months later,no cysticerci was found in all the pigs of the first group,in 5 pigs of the second group and in 2 pigs of the third group,respectively.These results revealed that the genetic engineering vaccine could play important role in the therapy to swine cysticercosis,and have better the effect in earlier therapy." @default.
- W2384164708 created "2016-06-24" @default.
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- W2384164708 date "2000-01-01" @default.
- W2384164708 modified "2023-09-24" @default.
- W2384164708 title "Immunotherapy for Swine Cysticercosis with the Genetic Engineering Vaccine" @default.
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