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- W2384164806 abstract "Objective: To investigate the effects of sesamin on lipidemia and the formation of non-alcoholic steatohepatitis(NASH).Methods: Hyperlipidemia rats model were established by feeding high lipid diet.The liver index,total cholesterol(TC),triglyeeride(TG),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),lipoprotein lipase(LPL),hepatic lipase(HL),apoproteinA1(ApoA1),apoproteinB100(ApoB100),superoxidedismutase(SOD)and malonaldehyde(MDA) were measured after administration with sesamin for 8 weeks.As well as,livers were taken for histopathological examination.Results: Therapeutic groups were significantly decreased TC,TG,LDL-C,ApoB100,MDA and liver index,increased HDL-C,HL,SOD(P0.05).The fatty degeneration and steatosis in liver were ameliorated by sesamin.Conclusion: Sesamin can remarkably modulate lipidemia and cure the NASH.Its mechanism is probably mediated through regulating lipids metabolism and anti-oxidation." @default.
- W2384164806 created "2016-06-24" @default.
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- W2384164806 date "2009-01-01" @default.
- W2384164806 modified "2023-09-25" @default.
- W2384164806 title "Effects of Sesamin on Lipidemia and Non-alcoholic Steatohepatitis in Hyperlipidemia Rats" @default.
- W2384164806 hasPublicationYear "2009" @default.
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