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- W2384182007 abstract "Aim: To investigate the effect of massive demineralized osteoarticular allograft transplantation in repair of segmental osteoarticular defects. Methods: A twenty millimeter osteoarticular defect with the periosteum was created in the proximal part of radius in New Zealand white rabbits. The defects were transplanted with demineralized osteoarticular allograft and osteoarticular autograft, and ungrafted, respectively. The healing of defects were then assessed by serial radiographic and histologic studies, and biomechanical tests 2 to 24 weeks after surgery. Results: The creeping appositional newly formed bone and cartilage slowly invaded and replaced the osteoarticular allograft after demineralized osteoarticular allograft transplant. The regenerated bone and cartilage more closely resembled normal bone and cartilaege, and its machanical properties were comparable to normal bone. The healing process of the osteoarticular autograft was basically similar to that of fracture. No newly formed bone and cartilage were seen in the ungrafted group 24 weeks after surgery. Conclusion: The demineralized osteoarticular allograft has low antigenicity and highly bone inducing properties, and is able to induce the host to regenerate articular cartilage. It may be an ideal material available for clinical use in reconstruction of segmental osteoarticular defect." @default.
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- W2384182007 date "1997-01-01" @default.
- W2384182007 modified "2023-09-26" @default.
- W2384182007 title "Massive Demineralized Osteoarticular Allograft Transplantation in Repair of Segmental Osteoarticular Defects in Rabbits" @default.
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