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- W2384200511 abstract "[Objective] To observe the effects of blood-activating and stasis-removing (BASR) herbs on the proliferation and apoptosis of gastric mucosa cells (GMC) in experimental chronic atrophic gastritis (CAG) rats. [Methods] CAG rat models were established with comprehensive method and then were given BASR herbs. Argyrophilic protein of nucleolar organizer regions ( AgNOR) count was carried out after silver nitrate staining. The expression of proliferating cell nuclear antigen (PCNA) was examined with immunohistochemical method and apoptosis was detected by in-situ cell-end labeling method. [Results] The number of AgNOR and the indexes of PCNA and apoptosis were increased in CAG model rats ( P 0.01 as compared with those in normal rats) and then were decreased after the adminstration of BASR herbs ( P 0.05 or P 0.01 as compared with those in model rats). [Conclusion] The down-regulatory effect of BASR herbs on the proliferation and apoptosis of GMC may be one of its preventive and therapeutic mechanisms for CAG." @default.
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- W2384200511 date "2003-01-01" @default.
- W2384200511 modified "2023-09-28" @default.
- W2384200511 title "Effect of Blood-activating and Stasis-removing Herbs on Proliferation and Apoptosis of Gastric Mucosa Cells in Experimental Chronic Atrophic Gastritis Rats" @default.
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