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- W2384222247 abstract "Aim To explore the administration method and lowest dose of megestrol acetate to achieve the safety and effectiveness in the treatment of simple and complex hyperplasia of endometrium(EH).Methods 22 cases of EH were analyzed retrospectively from 2008 to 2009 with 15 to be simple EH,and 7 complex EH.Within the simple EH group,8 cases were given megastrol acetate with 10 mg·d-1,and 7 cases were given 20 mg·d-1.In the meanwhile,3 cases were given 20 mg·d-1 and 4 cases were given 40 mg·d-1 for the complex EH group.Results After the treatment of megestrol acetate,1 simple EH case with 20 mg·d-1 was effective,1 simple EH case with 20 mg·d-1 was not effective,the rest 20 cases were relieved.The relieving rate was 90.91%,the overall effective rate(including significantly relieved ones and effective ones)was 95.45%,with 100% overall effective rate and relieved rate for complex EH cases.There was no significant difference between the two types of EH and doses.The average response time of the simple EH group for the low and high dose was 4.0 months and 4.5 months,respectively.The average response time of the complex EH group for the low and high dose was 4.3 months and 4.0 months,respectively.Conclusion When the outcome proves insignificant between different doses for the same type of EH,clinical treatment should make a balance between the dose and treating time to insure the safety of drug administration." @default.
- W2384222247 created "2016-06-24" @default.
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- W2384222247 date "2011-01-01" @default.
- W2384222247 modified "2023-09-24" @default.
- W2384222247 title "Dose of megestrol acetate in the treatment of hyperplasia of endometrium" @default.
- W2384222247 hasPublicationYear "2011" @default.
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