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- W2384235513 abstract "To improve the yield of S-adenosyl-L-methionine(SAM) by feeding methionine as precursor during the fermentation of Saccharomyces cerevisiae SAM-J5E-4,the effects of feeding strategies and the amount of different kinds of methionine on the production of SAM were investigated in 10 L fermentator,respectively.The results indicated that feeding D-or L-methionine during the fermentation,the accumulation of SAM reached 1.53 g/L and 4.66 g/L,in comparison with 0.38 g/L of the control.DL-methionine was the most suitable precursor for the accumulation of SAM.When the precursor amino acid was fed at a rate of 4 g/L/h for 5 h,the maximum yield of 5.28 g/L and more than 120 g/L of biomass were obtained.The feeding of DL-methionine during the fermentation could obviously enhance the productivity of SAM." @default.
- W2384235513 created "2016-06-24" @default.
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- W2384235513 date "2011-01-01" @default.
- W2384235513 modified "2023-09-24" @default.
- W2384235513 title "Effect of feeding DL-methionine as precursor on the production of S-adenosyl-L-methionine" @default.
- W2384235513 hasPublicationYear "2011" @default.
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