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- W2384247096 abstract "Objective To comparing the effect of the treatment of autologus dendritic cells(DCs) vaccine on the immune status of nasopharyngeal carcinoma(NPC) patients.Methods Twenty NPC patients were included in this study.In the control group patients were treated with radioactive therapy and in the treatment group patients were treated with DCs vaccine after the radioactive therapy(hypodermic injection 4 times).The T cell subtype,the lever of cytokines in the serum were detected in the treatment group during the whole treatment process.Results Patients in the DC treated group after vaccination all have improvements on quality of life in different extend.The T cell subtype such as CD3+,CD3+CD4+,CD4+/CD8+,NK and the serous cytokines including IL-2,IL-12,TNF-α and IFN-γ,also have a significant rising(P0.05).Conclusion Autologous DCs immunotherapy can improve the immune level of NPC patients.The level of cytokines in the serum of NPC patients after vaccination has a significant rising.This founding shows that DC immunotherapy induces the Th1 type response in NPC patients,and improves the anti-tumor ability." @default.
- W2384247096 created "2016-06-24" @default.
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- W2384247096 date "2010-01-01" @default.
- W2384247096 modified "2023-09-26" @default.
- W2384247096 title "The Change of Immune Status in Nasopharyngenl Carcinomal Patients with the Treatment of Autologus Dendritic Cells Vaccine" @default.
- W2384247096 hasPublicationYear "2010" @default.
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