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- W2384247178 abstract "Objective To explore the expression and analyze their relationship of HER-2, PRL, ER, VEGF and E-cadherin in invasive ductal carcinoma of breast. Methods The expression of ER, PRL, HER-2, VEGF and Ecadherin were evaluated by immunohistochemistry (SP method) in 55 cases with invasive ductal carcinoma of breast. Results The positive rates of ER, PRL, HER-2, VEGF and E-cadherin in 55 cases with invasive ductal carcinoma of breast were 61.82%, 58.18%, 38.18%, 36.36% and 30.90% respectively. The positive hyper-expression rates of ER, PRL, HER-2, VEGF and E-cadherin were 66.76%, 71.42%, 42.86%, 66.67% and 45.00% respectively in breast cancer cases with lymph node metastasis. The expression of VEGF in lymph node metastasis group was significantly higher than that of the non-transfer group (χ2=13.48,P0.05). HER-2 expression and PRL expression was negatively correlated (r =0.87, P 0.05), while ER and PRL was positive correlated (r = 0.55, P 0.05). Conclusions ER, PRL, HER-2, VEGF, E-cadherin can be used to guide clinical treatment and diagnosis in patients with invasive ductal carcinoma of breast." @default.
- W2384247178 created "2016-06-24" @default.
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- W2384247178 date "2010-01-01" @default.
- W2384247178 modified "2023-09-27" @default.
- W2384247178 title "Expression of ER, PRL, HER-2, VEGF and E-cadherin in invasive ductal carcinoma of breast" @default.
- W2384247178 hasPublicationYear "2010" @default.
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