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- W2384251311 abstract "The 140 patients with congestive heart failure (CHF) were equally divided into 2 groups at random. Group A received captopril 12.5 mg tid for 2 wk-3 mo; group B received nifedipine 10 mg tid for 2 wk-3 mo. After treatment the plasma renin activity (PRA) increased more in group B as compared with group A (P 0. 01). Angiotensin II (ACT H ), aldosterone and product of mean arterial pressure and heart rate (BP X HR) decreased and ejection fraction (EF) increased in group A as compared with group B (P 0. 05, 0. 01). The percentage of improved cardiac function of group A (90%) was higher than that of group B (71%) (P0. 05); there was a negative correlation between ACT II and EF% in group A (r = -0.33, P0.01). It is suggested that captopril can decrease mortality and improve prognosis of patients with severe CHF." @default.
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- W2384251311 date "1993-01-01" @default.
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- W2384251311 title "Effects of captopril and nifedipine on pla'sma renin-angiotensin system in patients with congestive heart failure" @default.
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