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- W2384299475 abstract "OBJECTIVE To develop a preparation method for gentamycin hemostasia collagen sponge and the determination method for its in vitro drug release.METHODS Sustained-release collagen sponge was made by the glutaraldehyde polymerizing the purified collagen protein,chitosan solution and qentamycin Sulfate.Orthogonal test was designed to investigate the optimal formulation.Drug release was determined at 0,24,48,72,96,120,144 h by the bioassay method.RESULTS The release rate at 24 h was 1 000-1 220 u·mL-1,280-340 u·mL-1 at 72 h,130-170 u·mL-1 at 120 h.CONCLUSION The hemostasia collagen sponge can be prepared and the method of determining drug release is established." @default.
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- W2384299475 date "2007-01-01" @default.
- W2384299475 modified "2023-09-23" @default.
- W2384299475 title "Study on the preparation and in vitro drug release of gentamycin hemostasia collagen sponge" @default.
- W2384299475 hasPublicationYear "2007" @default.
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