Matches in SemOpenAlex for { <https://semopenalex.org/work/W2384338443> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2384338443 abstract "Objective To explore the formation of cellular phagosome,fusion of phagusome and lyso- some,and ultrastructure changes in Leptospira-infected cells.Methods Mouse mononuclear-macrophnge like cell J774A.1 and monkey kidney fibroblast Cos-7 were infected with Leptospira interrogans serogroup Icterohaemor- rhagiae serovar Lai strain 56601.The formation of cellular phagosome and ultrastructure changes in the Leptospira- infection J774A.1 cells and Cos-7 cells were observed in EM.By using double immunofluorescence method and la- ser scanning confncal microscopy,the fusion of cellular Leptospira-contained phagosome with lysosome was ob- served.Results The cytoplasmic Leptospira-contained phagusomes were enclosed by membrane in J774A.1 cells at the 30 min and in Cus-7 cells at the 15 min after infection of L.interrogans strain 56601.Leptospira in the pha- gosomes maintained their original physiological curves.The membrane of Leptospira-contained phagusomes in Cos- 7 cells in 2 h after infection of L.interrogans strain 56601 became disappeared whereas no similar phenomenon in Leptospira-infected J774A.1 cells could be found.The co-lucaliztion of Leptospira-contained phagosomes and lyso- somes in J774A.1 cells occurred,indicating the fusion of phagosome and lysosome.The Leptospira-infected J774A.1 cells showed ultrastructural pathological changes such as chromatin condensation to form nucleic apoptotic body-like structure,vacuolar degeneration and swelling mituchondrion,whereas no ultrastructural pathological change in the Leptospira-infected Cos-7 cells was presented.Conclusion The cellular phagosomes can quickly form in J774A.1 and Cus-7 cells infected with Leptospira,which may be related to the expression products of lep- tuspiral typeⅢsecretary system.The Leptospira-contained phagosomes in J774A.1 cell can fuse with lysosome. There are remarkably different disappearance of the Leptospira-contained phagosome membrane and the ultrastruc- tural changes in different host cells." @default.
- W2384338443 created "2016-06-24" @default.
- W2384338443 creator A5003180460 @default.
- W2384338443 date "2007-01-01" @default.
- W2384338443 modified "2023-09-24" @default.
- W2384338443 title "Formation of the Leptospira-contained phagosome and fusion of the phagosome and lysosome in Leptospira interrogans infected cells" @default.
- W2384338443 hasPublicationYear "2007" @default.
- W2384338443 type Work @default.
- W2384338443 sameAs 2384338443 @default.
- W2384338443 citedByCount "0" @default.
- W2384338443 crossrefType "journal-article" @default.
- W2384338443 hasAuthorship W2384338443A5003180460 @default.
- W2384338443 hasConcept C102568950 @default.
- W2384338443 hasConcept C10389963 @default.
- W2384338443 hasConcept C105702510 @default.
- W2384338443 hasConcept C160448771 @default.
- W2384338443 hasConcept C161478664 @default.
- W2384338443 hasConcept C181199279 @default.
- W2384338443 hasConcept C190062978 @default.
- W2384338443 hasConcept C2776026663 @default.
- W2384338443 hasConcept C2780216420 @default.
- W2384338443 hasConcept C2780542935 @default.
- W2384338443 hasConcept C55493867 @default.
- W2384338443 hasConcept C86803240 @default.
- W2384338443 hasConcept C87555872 @default.
- W2384338443 hasConcept C89423630 @default.
- W2384338443 hasConcept C95444343 @default.
- W2384338443 hasConceptScore W2384338443C102568950 @default.
- W2384338443 hasConceptScore W2384338443C10389963 @default.
- W2384338443 hasConceptScore W2384338443C105702510 @default.
- W2384338443 hasConceptScore W2384338443C160448771 @default.
- W2384338443 hasConceptScore W2384338443C161478664 @default.
- W2384338443 hasConceptScore W2384338443C181199279 @default.
- W2384338443 hasConceptScore W2384338443C190062978 @default.
- W2384338443 hasConceptScore W2384338443C2776026663 @default.
- W2384338443 hasConceptScore W2384338443C2780216420 @default.
- W2384338443 hasConceptScore W2384338443C2780542935 @default.
- W2384338443 hasConceptScore W2384338443C55493867 @default.
- W2384338443 hasConceptScore W2384338443C86803240 @default.
- W2384338443 hasConceptScore W2384338443C87555872 @default.
- W2384338443 hasConceptScore W2384338443C89423630 @default.
- W2384338443 hasConceptScore W2384338443C95444343 @default.
- W2384338443 hasLocation W23843384431 @default.
- W2384338443 hasOpenAccess W2384338443 @default.
- W2384338443 hasPrimaryLocation W23843384431 @default.
- W2384338443 hasRelatedWork W1496030547 @default.
- W2384338443 hasRelatedWork W1540194084 @default.
- W2384338443 hasRelatedWork W1973156989 @default.
- W2384338443 hasRelatedWork W1992078470 @default.
- W2384338443 hasRelatedWork W2010891060 @default.
- W2384338443 hasRelatedWork W2048119055 @default.
- W2384338443 hasRelatedWork W2055093384 @default.
- W2384338443 hasRelatedWork W2093725577 @default.
- W2384338443 hasRelatedWork W2093956473 @default.
- W2384338443 hasRelatedWork W2107584747 @default.
- W2384338443 hasRelatedWork W2111698215 @default.
- W2384338443 hasRelatedWork W2119057012 @default.
- W2384338443 hasRelatedWork W2119784689 @default.
- W2384338443 hasRelatedWork W2125983377 @default.
- W2384338443 hasRelatedWork W2127845652 @default.
- W2384338443 hasRelatedWork W2130338905 @default.
- W2384338443 hasRelatedWork W2139296084 @default.
- W2384338443 hasRelatedWork W2146950688 @default.
- W2384338443 hasRelatedWork W2166802926 @default.
- W2384338443 hasRelatedWork W2171324514 @default.
- W2384338443 isParatext "false" @default.
- W2384338443 isRetracted "false" @default.
- W2384338443 magId "2384338443" @default.
- W2384338443 workType "article" @default.