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- W2384343698 abstract "Objective: The aim of this article was to investigate expression of nm23 protein and correlation with the prognosis of breast cancer in stage I.Methods: Expression of nm23 protein in 112 primary breast cancer patients was detected by means of immunohisto chemical assays.Results:In the 112 cases,nm23 protein was lowly expressed in 50 cases(44.64%)and highly expressed in 62 cases(55.36%).It was found that the 15 year disease free survival(DFS)to be significantly better in patients with high nm23 expression compared with low nm23 expression(P0.05).And in the patients whose axillary lymph nodes were negative,expression level of nm23 protein was significantly correlated with 15 year DFS(P0.01).Conclusion:In breast cancer of stage I,the expression level of nm23 protein may play a part role in the distant diagnosis.Moreover,it advised that we should emphasize the therapy of the patients with low nm23 expression whose axillary lymph node are negative in order to increase the therapeutic level of stage I breast cancer." @default.
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- W2384343698 date "2002-01-01" @default.
- W2384343698 modified "2023-09-26" @default.
- W2384343698 title "Correlation between the expression of nm23 gene and the prognosis of breast cancer in stage I" @default.
- W2384343698 hasPublicationYear "2002" @default.
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