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- W2384364098 abstract "Objective: To study the clinical effect of combination of danshen and alprostadil(prostaglandin E1) to treat patients with diabetic nephropathy(DN). Methods: Seventy-two patients with DN were randomly divided into two groups: test group, using the drugs of danshen and alprostadil with routine antidia-betics, that was consisted of 40 patients, including 19 cases of initial DN and 21 cases of clinical DN;control group with routine antidiabetic only was consisted of 32 patients, initial and clinical DN patients were 15 and 17 respectively; the observed indicators were 24 h urine albumin eliminate rate, blood viscosity, erythrocyte collect index, total cholesterol, triglycerides, blood urea nitrogen and comparing the indicators change in two groups. Results: (1) After treatment with danshen and alprostadil, the level of 24 h urine albumin eliminate rate had evident descent than that of before in initial and clinical DN patients (P 0. 05--0.01), (2) Collect index, blood urea nitrogen had evident descent also than before treatment in test group and the mentioned above the level of control patients were higher than test group (P 0. 05-0. 01). In test group, the level of triglycerides and total cholesterol had some descent, but the difference had not statistic significance. Conclusions: The treated measure of combination danshen with alprostadil can descend the removal of urine albumin, and descend the level of blood viscosity, erythrocyte collect index, blood urea nitrogen in patients with DN and protect their kidney function and delay the disease development; this treated measure is safe and the effect is definite." @default.
- W2384364098 created "2016-06-24" @default.
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- W2384364098 date "2005-01-01" @default.
- W2384364098 modified "2023-09-24" @default.
- W2384364098 title "A clinical review of combination of danshen and alprostadil to treat diabetic nephropathy" @default.
- W2384364098 hasPublicationYear "2005" @default.
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