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- W2384366941 abstract "OBJECTIVE To study the protective effects of quercetin solid dispersion on acute hepatic injury induced by carbon tetrachloride (CCl4 ) in mice. METHODS Mice were pretreated intragastrically with quercetin solid dispersion for 7days, and acute hepatic injury was induced by intraperitoneal injection of CCl4 . The liver index and the levels of glutamic pyruvic transaminase ( GPT) , glutamic oxaloacetic transaminase (GOT) in serum and superoxide dismutase (SOD) , glutathione peroxidase (GSH-Px) and malondialdehtyde (MDA) in liver tissue were detected, and pathological changes of liver tissue were examined to evaluate hepatic injury. RESULTS Quercetin solid dispersion could significantly reduce liver index, the levels of serum GPT, GOT and hepatic MDA, increase hepatic SOD and GSH-Px, and promote the recovery of hepatic tissue injury. CONCLUSION Quercetin solid dispersion protects CCl4-induced actue hepatic injury and reduces oxidative stress in mice." @default.
- W2384366941 created "2016-06-24" @default.
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- W2384366941 date "2013-01-01" @default.
- W2384366941 modified "2023-09-23" @default.
- W2384366941 title "Effects of quercetin solid dispersion on oxidative stress of carbon tetrachloride inducing acute hepatic injury in mice" @default.
- W2384366941 hasPublicationYear "2013" @default.
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