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- W2384397992 abstract "In order to investigate the inhibition of the extracts of prescription of 921 on prostate cancer cell proliferation in vitro and tumor growth in vivo.The authors use the methods as follow:SRB assay was applied to examine the anti-proliferation of the extracts of prescription of 921 in vitro both on human cancer cell DU-145,PC-3m,EJ and mice prostate cancer TRAMP-C2.The experimental implanted tumor mice model Hepatoma(H22),Sarcoma(S180),Prostate cancer(TRAMP-C2) and tumor nude mice model Prostate cancer(PC-3M) were used to evaluate its anti-tumor activity in vivo.Furthermore,it was also observed to enhance therapeutic effect when combined with cyclophosphamide(CTX) on S180.The results were:1) the extracts of prescription of 921 showed proliferation inhibitory activities on DU-145,PC-3M,EJ and TRAMP-C2 cell lines.2) It inhibited mice H22,S180,TRAMP-C2 and naked mice PC-3M when administered i.g.at 3.6～14.3 g/(kg·day) for 9 days.The extracts of prescription of 921 enhanced CTX's therapeutic effect and didn't enhance its toxicity.In summary,the extracts of prescription of 921 showed inhibitory activity on the growth of prostate cancer." @default.
- W2384397992 created "2016-06-24" @default.
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- W2384397992 date "2007-01-01" @default.
- W2384397992 modified "2023-09-26" @default.
- W2384397992 title "Anticancer Activity on Prostate Cancer of the Extracts of Prescription of TCM 921" @default.
- W2384397992 hasPublicationYear "2007" @default.
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