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- W2384429366 abstract "Objective To investigate the carcinogenesis and constructive mechanism of congenital choleduchal cyst.Methods I-type choleduchal cysts were divided into high-amylase cystic type,low-amylase cystic type and fusiform type.We used the immunohistochemistry method detected the expression of iNOS,p53,PCNA and TUNEL in the epithelial cells of choleduchal cysts.Results There were high expression of iNOS,p53,PCNA,TUNEL in the high-amylase cystic type and fusiform type,and low expression in the low-amylase type.P53protein was not detectable in all three groups.Conclusions The regurgitation of pancreatic juice into the biliary system may promot epithelial cell proliferation and apoptosis in the biliary tract,it play an important role in the induction of choleduchal cyst.Higher expression of NO and high proliferation activity of epithelial cells may be involved in the carcinogenesis of the choledochal cysts mucosa." @default.
- W2384429366 created "2016-06-24" @default.
- W2384429366 creator A5018330631 @default.
- W2384429366 date "2003-01-01" @default.
- W2384429366 modified "2023-09-27" @default.
- W2384429366 title "Study in the Relationship Between the Epithelial Cell Proliferation and Cyst Construction in the Congenital Choledochal Cyst." @default.
- W2384429366 hasPublicationYear "2003" @default.
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