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- W2384452481 abstract "Objective:To study the effect extracts from Xinjiang Coriopsis ticntoria flowers(CTF) on α-glucosidase activity.Method: Five extracts of CTF were prepared by water extraction and organic solvent abstraction.Including CTF ethylacetate extraction,CTF normal butyl alcohol extraction,CTF total flavanone,CTF water extraction and CTF neutral flavanone.The inhibitory effects of these extracts to α-glucosidase activity were investigated by in vitro enzymatic method;and akarbose was used as positive reference substance.Result: The extracts of CTF showed obviously inhibitory action against α-glucosidase activity in which 4 extracts have higher effects compared to those of acarbose,among them,the extract of CTF neutral flavanone was more effective for enzyme inhibition with a inhibitory rate of 87.26%.The CTF IC50 of the five extracts were: Acarbose IC50858.0 mg.L-1,CTF ethylacetate extraction IC50 12.5 mg.L-1,CTF normal butyl alcohol extraction IC50 139.5 mg.L-1,CTF total flavanone IC50 163.5 mg.L-1,CTF water extraction IC50 367.6 mg.L-1,CTF neutral flavanone IC50 5.8 mg.L-1.Conclusion: Coriopsis ticntoria flowers extracts had remarkable inhibitory effect to α-glucosidase activity.This finding provides important information for pharmacological screening of new anti-diabetic agent from CTF plant." @default.
- W2384452481 created "2016-06-24" @default.
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- W2384452481 date "2011-01-01" @default.
- W2384452481 modified "2023-09-25" @default.
- W2384452481 title "Effect of Extracts from Coriopsis ticntoria Flowers of Xinjiang Kunlun Mountain on α-glucosidase Activity" @default.
- W2384452481 hasPublicationYear "2011" @default.
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