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- W2384455943 abstract "Objective To evaluate coronary microcirculation endothelial function in patients who had high risk factors for coronary artery disease but negative results in coronary arteriongraphy by cold pressor test(CPT)echocardiography and coronary flow imaging.Methods Fourty subjects with negative results by coronary arteriongraphy were divided into two groups.Group I was20 subjects without risk factors for coronary artery disease,and group II was 20 subjects with high risk factors for coronary artery disease.The left main coronary(LMC)diameter and the coronary peak velocity(CPV)were measured on rest condition,CPT and after taking sublingual nitroglycerin in both groups respectively.The percentage changes of LMC diameter,CPV after CPT and nitroglycerin administration in two groups were calculated to assess the endothelium function.Results There was no significant difference in coronary diameter and basic value of peak value flow in two groups on rest condition(P0.05).After CPT,the percentage increase of LMC diameter and the CPV in group I was(4.53±2.65)% and(23.64±5.72)%,which were lower than those in group II,(11.37±3.29)% and(43.76±4.28)(P0.05).After nitroglycerin administration,there was no significant difference between two groups(P0.05).Conclusion Coronary microcirculation endothelial dysfunction could be detected in groups with risk factors for coronary artery disease by cold pressor echocardiography,which is considered as an useful non-interventional method for clinical analysis,disease risk assessment and treatment." @default.
- W2384455943 created "2016-06-24" @default.
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- W2384455943 date "2009-01-01" @default.
- W2384455943 modified "2023-09-24" @default.
- W2384455943 title "Evaluation of coronary microcirculation endothelial function by cold pressor test echocardiography and coronary flow imaging" @default.
- W2384455943 hasPublicationYear "2009" @default.
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