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- W2384497686 abstract "Objective To explore clinical pathological characteristics and prognosis of gasitric carcinoma(GC) with high lever of alpha-fetoprotein(AFP).Methods 12 cases of gastric carcinoma patients has high lever of AFP among 140 cases,their clinical data were retrospectively analyzed.Results The alpha-fetoprotein level of 12 cases of gastric carcinoma has high lever of AFP was between 71.97~275691.6 μg/L.Pathological histology:low differentiated adenocarcinoma[58.3%(7/12)],tubular adenocarcinoma[25.0%(3/12)],hepatoid carcinomas[16.7%(2/12)].Tumors were mostly located in the antrum and stomach,which was 66.7%(8/12),cardiac was 33.3%(4/12).Clinical staging was for stage IV,and the liver hilar lymph node metastasis was 16.7%(2/12),liver metastasis was 25.0%(3/12),abdominal lymph node metastasis was 25.0%(3/12),liver metastasis with abdominal lymph node metastasis was 25.0%(3/12),other sites of metastasis was 8.3%(1/12).4 cases had postoperative recurrence and metastasis,average time of recurrence and metastasis after radical surgery was 7.7 months,the shortest metastasis appeared in 3 months,6 cases received palliative operation,2 cases did not undergo surgery.10 cases adopted different regimens of palliative chemotherapy.Survival period was 2 ~54 months,and the median survival time was 8 months.Conclusion Gasitric carcinoma with high lever of AFP of is a special clinical subtype,it has tendency of liver metastasis and(or) celiac metastasis with poor prognosis." @default.
- W2384497686 created "2016-06-24" @default.
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- W2384497686 date "2012-01-01" @default.
- W2384497686 modified "2023-09-28" @default.
- W2384497686 title "Clinical Analysis of 12 Cases of Gastric Carcinoma with High Lever of Alpha-fetoprotein" @default.
- W2384497686 hasPublicationYear "2012" @default.
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