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- W2384506402 abstract "Dipeptide Boc-Leu-N-Me-Leu-OBzl containing N-Me was synthesized with four different coupling reagents.After activated by coupling reagents such as DCC/HOBt、EDC/HOBt、EEDQ and DEPBT,the yield were 73.5%～92.8%,65.2%～85.9%,38.9%,87.8%,respectively.The yield was higher than any of other coupling reagents when the molar ratio of Boc-Leu-OH/ H-N-Me-Leu-OBzl/ DCC/HOBt was 2.0∶1.0∶2.0.Three stereoisomers were gotten by coupling reagent DCC/HOBt with high yield when the molar ratio was 2.0∶1.0∶2.0." @default.
- W2384506402 created "2016-06-24" @default.
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- W2384506402 date "2009-01-01" @default.
- W2384506402 modified "2023-09-23" @default.
- W2384506402 title "Four coupling reagents for synthesis of N-methyldipeptide" @default.
- W2384506402 hasPublicationYear "2009" @default.
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