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- W2384602812 abstract "Objective: To investigate the expression and clinical significance of PAI-1,u-PA,and VEGF in non Hodgkin lymphoma.Methods: The expression of PAI-1,u-PA,and VEGF were evaluated in 69 cases of non-Hodgkin lymphoma by means of immunohistochemistry.Results: The expression rate of PAI-1,u-PA,VEGF detected in non-Hodgkin lymphoma was 62.31%,44.93%,and 34.78%,respectively,which was higher than that in the normal lymph node specimen(P0.05).The expression of VEGF in advanced stage was markedly higher than that in early stage(P0.05).The expression of u-PA was higher in patients with general symptoms such as fever or body weight loss.The remission rate was significantly higher in u-PA-negative group and in VEGF-positive group respectively.The 3-year survival rate of patients with PAI-1 positive expression was lower(P0.05).There was no relationship among the expression of PAI-1,u-PA,and VEGF.Conclusion: The high expression of PAI-1,u-PA,and VEGF could be detected in non-Hodgkin lymphoma,and their expression has a close relation to the biological behavior characters of non-Hodgkin lymphoma.PAI-1,u-PA,and VEGF of non-Hodgkin lymphoma should be detected together for the general evaluation." @default.
- W2384602812 created "2016-06-24" @default.
- W2384602812 creator A5062542288 @default.
- W2384602812 date "2009-01-01" @default.
- W2384602812 modified "2023-09-25" @default.
- W2384602812 title "Expression and Significance of PAI-1,u-PA,and VEGF in Non-Hodgkin Lymphoma" @default.
- W2384602812 hasPublicationYear "2009" @default.
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