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- W2384652171 abstract "Aim To study the resistance and carbapenemase genotype of imipenem-resistant Acinetobacter baumannii(IRAB)isolates in our hospital.Methods Thirty-five non-repetitive isolates of IRAB were collected.The drug resistance was detected by Kirby-Bauer test and E-test.The modified Hodge and the ethylenediaminetetraacetic acid(EDTA)-disk synergy test were performed for screening carbapenemase and metallo-β-lactamase production.PCR was performed to determine OXA-23,OXA-24,OXA-58,IMP and VIM carbapenemase gene.Results All isolates showed very high resistance(70%) to common antimicrobial agents concluding β-lactams,a part of aminoglycosides,quinolones,sulfa drugs,and high susceptibility(70%)to amikacin,sulperazon and polymyxin B.All of the 35 isolates(100%) showed positive results in the modified Hodge test and negative results in the EDTA-disk synergy test.They all(100%) possessed the encoding gene for an OXA-23 carbapenemase.Conclusion The resistance of IRAB was very serious.OXA-23 gene are the most popular carbapenemase coding genes in our hospital." @default.
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- W2384652171 date "2011-01-01" @default.
- W2384652171 modified "2023-09-23" @default.
- W2384652171 title "The carbapenemase genotype of imipenem-resistant Acinetobacter baumannii isolates" @default.
- W2384652171 hasPublicationYear "2011" @default.
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