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- W2384696046 abstract "Objective To investigate the change of serum adiponectin level in different stages of diabetic retinopathy(DR).Methods 113 patients with type 2 diabetes mellitus(DM),including 30 patients without DR(DM group),45 patients complicating with background DR(BDR group) and 38 complicating with proliferative DR(PDR group),and 30 healthy controls(served as control group) were enrolled in this study.Enzyme-linked immunosorbent assay(ELISA) was applied to measuring serum level of adiponectin.Results(1) The serum level of adiponectin in DM group was significantly lower than that in control group(P0.05).There were statistical difference of serum adiponectin level between BDR group and DM group as well as control group(P0.05 and 0.01 respectively).Serum adiponectin level changed remarkably in PDR group compared with respective one in BDR group,DM group and control group(P0.05 or 0.01).(2) Correlation analysis revealed serum adiponectin level was closely negative correlation with systolic blood pressure(SBP),glycosylated hemoglobin,triglyeride(TG),total cholesterol(TC),and low density lipoprotein-cholesterol(LDL-C),but significantly positive correlation with high density lipoprotein-cholesterol(HDL-C).Conclusion Serum level of adiponectin in patients with type 2 diabetes mellitus declines significantly,especially for patients complicating with diabetic retinopathy.Adiponectin type may be used as an reliable clinical markers for assessing the severity of DR complicated to type 2 diabetes mellitus." @default.
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- W2384696046 date "2007-01-01" @default.
- W2384696046 modified "2023-09-23" @default.
- W2384696046 title "Investigation on serum level of adiponectin in patients with type 2 diabetic retinopathy" @default.
- W2384696046 hasPublicationYear "2007" @default.
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