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- W2384734679 abstract "Objective To investigate expression of glycogen synthase kinase(GSK)-3β and phosphorylation GSK-3β (p-GSK-3β) in the anterior temporal neocortex in patients with refractory epilepsy(RE). Methods Expression of GSK-3β and p-GSK-3β were detected by RT-PCR, FQ-PCR, Western Blot and immunohistochemistry in the anterior temporal cortices of 36 RE cases. 8 patients without RE had been used as the controls. Results Compared with control group,the expression of GSK-3β mRNA and protein were significant higher(allP0.05) and p-GSK-3β was down-reuglated (P0.05) in the anterior temporal neocortex in RE group. Conclusion The abnormal expression of GSK-3β and p-GSK-3β may be indicated the pathologic role in RE." @default.
- W2384734679 created "2016-06-24" @default.
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- W2384734679 date "2008-01-01" @default.
- W2384734679 modified "2023-09-24" @default.
- W2384734679 title "Expression of glycogen synthase kinase-3β and its phosphorylated product in the anterior temporal neocortex in patients with refractory epilepsy" @default.
- W2384734679 hasPublicationYear "2008" @default.
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