Matches in SemOpenAlex for { <https://semopenalex.org/work/W2384736098> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2384736098 abstract "Objective To explore the effects of adrenomedullin (AM) and AM receptor inhibitor (AM22-52) on the activity of the protein kinase B (PKB) in human ovarian epithelial cancer cell line CAOV3. Methods The activity of PKB in CAOV3 cells induced by different concentration of AM and AM22-52 was detected by Western blot. Results There was no obvious difference for the expression of total-PKB (t-PKB) between control group and experiment groups (AM group or AM22-52 group). AM (1×10-9～1×10-6mol/L) could improve the activity of p-PKB in CAOV3 significantly, AM22-52 (1×10-9～ 1×10-6mol/L) could suppress the activity of p-PKB, and both with a dose-dependent manner ( 0.05). Conclusion The results of activation of PKB signal pathway by AM in CAOV3 and inhibition of the signal pathway by AM22-52 might provide a new route for the treatment of ovarian cancer." @default.
- W2384736098 created "2016-06-24" @default.
- W2384736098 creator A5017360203 @default.
- W2384736098 date "2009-01-01" @default.
- W2384736098 modified "2023-09-26" @default.
- W2384736098 title "Effects of AM and AM22-52 on Activity of PKB in Human Ovarian Epithelial Cancer Cells Line CAOV3" @default.
- W2384736098 hasPublicationYear "2009" @default.
- W2384736098 type Work @default.
- W2384736098 sameAs 2384736098 @default.
- W2384736098 citedByCount "0" @default.
- W2384736098 crossrefType "journal-article" @default.
- W2384736098 hasAuthorship W2384736098A5017360203 @default.
- W2384736098 hasConcept C104317684 @default.
- W2384736098 hasConcept C11960822 @default.
- W2384736098 hasConcept C121608353 @default.
- W2384736098 hasConcept C126322002 @default.
- W2384736098 hasConcept C134018914 @default.
- W2384736098 hasConcept C153911025 @default.
- W2384736098 hasConcept C170493617 @default.
- W2384736098 hasConcept C184235292 @default.
- W2384736098 hasConcept C185592680 @default.
- W2384736098 hasConcept C2776415932 @default.
- W2384736098 hasConcept C2777152744 @default.
- W2384736098 hasConcept C2780427987 @default.
- W2384736098 hasConcept C502942594 @default.
- W2384736098 hasConcept C55493867 @default.
- W2384736098 hasConcept C71924100 @default.
- W2384736098 hasConcept C75217442 @default.
- W2384736098 hasConcept C86803240 @default.
- W2384736098 hasConceptScore W2384736098C104317684 @default.
- W2384736098 hasConceptScore W2384736098C11960822 @default.
- W2384736098 hasConceptScore W2384736098C121608353 @default.
- W2384736098 hasConceptScore W2384736098C126322002 @default.
- W2384736098 hasConceptScore W2384736098C134018914 @default.
- W2384736098 hasConceptScore W2384736098C153911025 @default.
- W2384736098 hasConceptScore W2384736098C170493617 @default.
- W2384736098 hasConceptScore W2384736098C184235292 @default.
- W2384736098 hasConceptScore W2384736098C185592680 @default.
- W2384736098 hasConceptScore W2384736098C2776415932 @default.
- W2384736098 hasConceptScore W2384736098C2777152744 @default.
- W2384736098 hasConceptScore W2384736098C2780427987 @default.
- W2384736098 hasConceptScore W2384736098C502942594 @default.
- W2384736098 hasConceptScore W2384736098C55493867 @default.
- W2384736098 hasConceptScore W2384736098C71924100 @default.
- W2384736098 hasConceptScore W2384736098C75217442 @default.
- W2384736098 hasConceptScore W2384736098C86803240 @default.
- W2384736098 hasLocation W23847360981 @default.
- W2384736098 hasOpenAccess W2384736098 @default.
- W2384736098 hasPrimaryLocation W23847360981 @default.
- W2384736098 hasRelatedWork W1487471976 @default.
- W2384736098 hasRelatedWork W1993765367 @default.
- W2384736098 hasRelatedWork W2023861301 @default.
- W2384736098 hasRelatedWork W2033302109 @default.
- W2384736098 hasRelatedWork W2089655168 @default.
- W2384736098 hasRelatedWork W2351054891 @default.
- W2384736098 hasRelatedWork W2353473364 @default.
- W2384736098 hasRelatedWork W2355445911 @default.
- W2384736098 hasRelatedWork W2356658607 @default.
- W2384736098 hasRelatedWork W2356994458 @default.
- W2384736098 hasRelatedWork W2361454114 @default.
- W2384736098 hasRelatedWork W2364941454 @default.
- W2384736098 hasRelatedWork W2367966796 @default.
- W2384736098 hasRelatedWork W2368684521 @default.
- W2384736098 hasRelatedWork W2371971752 @default.
- W2384736098 hasRelatedWork W2377469204 @default.
- W2384736098 hasRelatedWork W2388792820 @default.
- W2384736098 hasRelatedWork W2392174477 @default.
- W2384736098 hasRelatedWork W2394153463 @default.
- W2384736098 hasRelatedWork W5161616 @default.
- W2384736098 isParatext "false" @default.
- W2384736098 isRetracted "false" @default.
- W2384736098 magId "2384736098" @default.
- W2384736098 workType "article" @default.