Matches in SemOpenAlex for { <https://semopenalex.org/work/W2384751145> ?p ?o ?g. }
- W2384751145 endingPage "242" @default.
- W2384751145 startingPage "235" @default.
- W2384751145 abstract "Neural circuits underlying male sexual function comprise several nuclei located in the brain and spinal cord. We have previously demonstrated in rats that the gastrin-releasing peptide (GRP) system influences spinal centers promoting penile reflexes. Moreover, a group of oxytocin (OXT) neurons, situated in the parvocellular part of the paraventricular nucleus of the hypothalamus, project into the spinal cord and control penile reflexes. Therefore, it has been hypothesized that OXT is transported by long descending paraventriculospinal pathways and activates proerectile spinal centers. Consequently, we have shown that in rats, axonal distribution of OXT in the lumbar spinal cord exhibits a male-dominant sexual dimorphism. Furthermore, OXT binding is observed in the spinal GRP neurons. Thus, OXT axons may secrete OXT from spinal axonal terminals and regulate male sexual function via an OXT receptor-mediated mechanism in spinal GRP neurons. Future studies should address the relationship between the hypothalamic OXT and spinal GRP systems. Identification of the male-specific brain-spinal cord neural circuit that regulates male sexual behavior may provide new avenues for therapeutic approaches to masculine reproductive dysfunction, including erectile dysfunction and/or ejaculation disorder." @default.
- W2384751145 created "2016-06-24" @default.
- W2384751145 creator A5004060857 @default.
- W2384751145 creator A5068335003 @default.
- W2384751145 date "2015-01-01" @default.
- W2384751145 modified "2023-10-18" @default.
- W2384751145 title "Oxytocin and the Gastrin-Releasing Peptide System in the Spinal Cord: Implications for Male Sexual Problems" @default.
- W2384751145 cites W1515940638 @default.
- W2384751145 cites W1530855819 @default.
- W2384751145 cites W1553498318 @default.
- W2384751145 cites W1565230790 @default.
- W2384751145 cites W1579449310 @default.
- W2384751145 cites W1594528037 @default.
- W2384751145 cites W1672797979 @default.
- W2384751145 cites W1965670118 @default.
- W2384751145 cites W1967304600 @default.
- W2384751145 cites W1970747872 @default.
- W2384751145 cites W1973914400 @default.
- W2384751145 cites W1981502226 @default.
- W2384751145 cites W1985658207 @default.
- W2384751145 cites W1988111671 @default.
- W2384751145 cites W1989818009 @default.
- W2384751145 cites W1990168204 @default.
- W2384751145 cites W1992996125 @default.
- W2384751145 cites W1993825767 @default.
- W2384751145 cites W1995114201 @default.
- W2384751145 cites W1997499726 @default.
- W2384751145 cites W2006268333 @default.
- W2384751145 cites W2008804935 @default.
- W2384751145 cites W2011595502 @default.
- W2384751145 cites W2014539594 @default.
- W2384751145 cites W2015310897 @default.
- W2384751145 cites W2018203694 @default.
- W2384751145 cites W2019599063 @default.
- W2384751145 cites W2031526448 @default.
- W2384751145 cites W2035261481 @default.
- W2384751145 cites W2039443858 @default.
- W2384751145 cites W2040837198 @default.
- W2384751145 cites W2054502350 @default.
- W2384751145 cites W2056436647 @default.
- W2384751145 cites W2058487977 @default.
- W2384751145 cites W2059337320 @default.
- W2384751145 cites W2070810698 @default.
- W2384751145 cites W2075447738 @default.
- W2384751145 cites W2075567911 @default.
- W2384751145 cites W2079821310 @default.
- W2384751145 cites W2083015625 @default.
- W2384751145 cites W2085948837 @default.
- W2384751145 cites W2088051038 @default.
- W2384751145 cites W2109390122 @default.
- W2384751145 cites W2139299578 @default.
- W2384751145 cites W2142914456 @default.
- W2384751145 cites W2144908726 @default.
- W2384751145 cites W2148544989 @default.
- W2384751145 cites W2315113397 @default.
- W2384751145 cites W2324493973 @default.
- W2384751145 cites W2408038348 @default.
- W2384751145 cites W2410174595 @default.
- W2384751145 doi "https://doi.org/10.4036/iis.2015.b.08" @default.
- W2384751145 hasPublicationYear "2015" @default.
- W2384751145 type Work @default.
- W2384751145 sameAs 2384751145 @default.
- W2384751145 citedByCount "0" @default.
- W2384751145 crossrefType "journal-article" @default.
- W2384751145 hasAuthorship W2384751145A5004060857 @default.
- W2384751145 hasAuthorship W2384751145A5068335003 @default.
- W2384751145 hasBestOaLocation W23847511451 @default.
- W2384751145 hasConcept C118303440 @default.
- W2384751145 hasConcept C126322002 @default.
- W2384751145 hasConcept C134018914 @default.
- W2384751145 hasConcept C169760540 @default.
- W2384751145 hasConcept C170493617 @default.
- W2384751145 hasConcept C181612422 @default.
- W2384751145 hasConcept C186706434 @default.
- W2384751145 hasConcept C2776176026 @default.
- W2384751145 hasConcept C2776370428 @default.
- W2384751145 hasConcept C2776998989 @default.
- W2384751145 hasConcept C2777003273 @default.
- W2384751145 hasConcept C2777812360 @default.
- W2384751145 hasConcept C2778448772 @default.
- W2384751145 hasConcept C2780775167 @default.
- W2384751145 hasConcept C2909382400 @default.
- W2384751145 hasConcept C529278444 @default.
- W2384751145 hasConcept C71924100 @default.
- W2384751145 hasConcept C86803240 @default.
- W2384751145 hasConceptScore W2384751145C118303440 @default.
- W2384751145 hasConceptScore W2384751145C126322002 @default.
- W2384751145 hasConceptScore W2384751145C134018914 @default.
- W2384751145 hasConceptScore W2384751145C169760540 @default.
- W2384751145 hasConceptScore W2384751145C170493617 @default.
- W2384751145 hasConceptScore W2384751145C181612422 @default.
- W2384751145 hasConceptScore W2384751145C186706434 @default.
- W2384751145 hasConceptScore W2384751145C2776176026 @default.
- W2384751145 hasConceptScore W2384751145C2776370428 @default.
- W2384751145 hasConceptScore W2384751145C2776998989 @default.
- W2384751145 hasConceptScore W2384751145C2777003273 @default.
- W2384751145 hasConceptScore W2384751145C2777812360 @default.
- W2384751145 hasConceptScore W2384751145C2778448772 @default.