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- W2384754004 abstract "Objective To explore the expressions of filamin A(FLNA)and cyclin D1 in breast infiltrative ductal carcinoma.Methods The expressions of FLNA and cyclin D1 in 68 samples of breast infiltrative ductal carcinoma(group A)and 30 samples of breast non-carcinoma tissues(group C)were detected by immunohistochemistry.The correlation of FLNA and cyclin D1 expressions and the relationship of FLNA and cyclin D1 expressions with clinical pathological features in group A were analyzed.Results The positive expression rates of FLNA and cyclin D1 in group A were 50.0% and 48.5%,respectively,which were closely related to lymph node metastasis and TNM stage(P0.01 and P0.05).The expressions of FLNA and cyclin D1 in group C were negative or weak positive.The expression of FLNA was positively correlated with that of cyclin D1 in group A(r=0.324,P0.01).Conclusion FLNA may play an important role in the development and progression of breast infiltrative ductal carcinoma by upregulating cyclin D1 expression." @default.
- W2384754004 created "2016-06-24" @default.
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- W2384754004 date "2015-01-01" @default.
- W2384754004 modified "2023-09-24" @default.
- W2384754004 title "Expressions of FLNA and cyclin D1 in breast infiltrative ductal carcinoma" @default.
- W2384754004 hasPublicationYear "2015" @default.
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