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- W2384770281 abstract "Objective Recruitment is considered an important mechanism for mesenchymal stem cells(MSCs) to repair and construct damaged tissues.This study was to observe if mesenchymal stem cells play important roles in chemotaxis of endothelial progenitor cells(EPCs) in vitro.Methods The skin MSCs of fetal rat and rat EPCs were isolated and cultured.The expressions of SDF-1 and CXCR4 were detected by immunohistochemistry.Migration experiments were used to observe whether MSCs affect the migration of EPCs.Results According to the results of immunohistochemistry,MSCs and EPCs can express SDF-1 and CXCR4 respectively.MSCs can promote the migration of EPCs and if the SDF-1 expression was blocked,this promoting effect would be suppressed(P0.05).Conclusion It is confirmed that MSCs can promote chemotaxis of EPCs in vitro." @default.
- W2384770281 created "2016-06-24" @default.
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- W2384770281 date "2011-01-01" @default.
- W2384770281 modified "2023-09-23" @default.
- W2384770281 title "Effects of skin-derived mesenchymal stem cells on recruitment of endothelial progenitor cells in vitro" @default.
- W2384770281 hasPublicationYear "2011" @default.
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