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- W2384807002 abstract "Objective To investigate the quality and clinical effect of leucocyte-depleted blood components,especially leukocyte-depleted suspension RBC.Method The physicochemical indexes of the following specimen were determined: 91 bags of whole blood,90 bags of leukocyte-depleted whole blood,76 bags of suspension RBC,82 bags of leukocyte-depleted suspension RBC.The clinical data of 145 suspension RBC transfusion recipients and 329 leukocyte-depleted suspension RBC transfusion recipients was analyzed retrospectively.Results Hemolysis wasn't observed in leukocyte depleted blood.The changes of the level of FHb,pH,K+,and Na+ in blood had no statistical differences,which were(0.19±0.10) g/L,6.88±0.06,(19.78±4.01) mmol/L,and(141.62±8.10) mmol/L,respectively.The content of FHb of leukocyte depleted blood made by seamless connection method and continuous bag filter method was(0.10±0.097)g/L and(0.16±0.13)g/L,respectively(P0.05).The volume and Hct of suspension RBC and leukocyte depleted suspension RBC made by the above two methods were(144.01±11.54) ml,(152.45±15.39) ml,(158.71±10.69) ml and 0.48±0.03,0.50±0.03,0.53±0.05,respectively,and all the differences had statistical significance(P0.05).The leucocyte clearance rate of filtration method was 3 log10,and the residual leucocyte was 10-6.The blood transfusion data of surgical,internal medical and non-haemorrhagic patients revealed that the effect of leukocyte-depleted suspension RBC was better than that of the suspension RBC.RBC and Hb in the three kinds of patients who received leukocyte-depleted suspension RBC and suspension RBC were(0.55 vs 0.42)×1012/L,(0.37 vs 0.28)×1012/L,(0.62 vs 0.50)×1012/L,and(14.5 vs 13.5)×g/L,(12 vs 8)×g/L,(18.43 vs 15.86)×g/L,respectively.Conclusion The quality of leukocyte depleted blood and suspension RBC,made by seamless connection method and continuous bag filter method,was stable and reliable.The blood transfusion effect of leukocyte-depleted suspension RBC was better than that of the suspension RBC." @default.
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- W2384807002 date "2009-01-01" @default.
- W2384807002 modified "2023-09-24" @default.
- W2384807002 title "Quality and clinical application of leukocyte-depleted blood components" @default.
- W2384807002 hasPublicationYear "2009" @default.
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