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- W2384807695 abstract "Objective To evaluate the relationship between respiratory tract inflammation and interleukin-8,tumor necrosis factor-α,neutrophil in the sputum and the relationship between these factors and smoking in smokers.Methods 30 healthy smokers and 30 healthy nonsmokers were chosen.The sputum samples were collected by inducing method.Cells in the sputum were examined by microscopy.The levels of interleukin-8 and tumor necrosis factor-α in fluid-phase of sputum were determined by enzyme-linked immunosorbent assay(ELISA).Results A increased levels of interleukin-8 and neutrophil proportion were showed in the sputum of healthy smoking group compared with those of healthy nonsmoking group(P0.01,P0.05).As for the levels of tumor necrosis factor-α,no significant difference was seen between healthy smoking group and healthy nonsmoking group(P0.05).There was no significant difference between the level of interleukin-8 in the cases(smoking index400)and that in the cases(smoking index ≤400)(P0.05).The level of interleukin-8 in the sputum showed a positive correlation with neutrophil proportion(r=0.544).Conclusion Neutrophil,IL-8 in the sputum are associated with respiratory tract inflammation in the healthy smokers,smoking is an important factor in the inflammation." @default.
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- W2384807695 date "2007-01-01" @default.
- W2384807695 modified "2023-09-26" @default.
- W2384807695 title "Relationship between Respiratory Tract inflammation and Interleukin-8,Tumour Necrosis Factor-α in Sputum of Smokers" @default.
- W2384807695 hasPublicationYear "2007" @default.
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