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- W2384815041 abstract "Purpose: To evaluate the feasibility of diffusion-weighted(DW) and blood oxygenation level-dependent(BOLD) magnetic resonance imaging(MRI) in patients with renal allograft,and to compared the ADC and R2* values of the cortex and medulla of the transplanted kidneys with the values of the native kidneys of normal healthy volunteers at a 3.0T MR scanner.To preliminarily differentiate chronic allograft nephropathy(CAN) from normal transplanted kidney.Methods: Sixteen patients with normal renal function(n=8) or chronic allograft nephropathy(n=8) and 16 age and gender matched healthy volunteers underwent DWI and BOLD MR imaging at a 3.0T scanner.Circular regions of interest(ROI) were delineated in the renal cortex and medulla on ADC maps and R2* maps on the workstation.The statistical analyses of all the results were performed with software SPSS(version 11.0).Results: The SNRs of transplanted kidney could meet the request of imaging.Baseline and the range of ADC values and R2* values achieved in patients at 3.0T scanner were higher than those at 1.5T scanner before.The cortical ADC(CADC),medullary R2*(MR2*) and medullary to cortical R2* ratios(MCR2*) were significant lower in CAN kidneys than in normal transplanted kidneys.Conclusion: At 3.0T MR scanner,DW and BOLD MRI are feasible and benefit both in native renal and in renal allograft.fMRI can be used to non-invasively evaluate the renal function earlier and help to differentiate from CAN." @default.
- W2384815041 created "2016-06-24" @default.
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- W2384815041 date "2012-01-01" @default.
- W2384815041 modified "2023-09-23" @default.
- W2384815041 title "Study of Transplanted Kidneys by Diffusion-weighted and BOLD MRI at 3T" @default.
- W2384815041 hasPublicationYear "2012" @default.
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