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- W2384877417 abstract "Objective:To explore the correlation among platelet activation factor CD63?CD62P and the stage?stratification of risk in essential hypertension(EH)and study an effect of angiotensin Ⅱ type 1 receptor antagonism(losartan) on them.Methods:CD63?CD62P were detected by flow cytometry in 86 patients with hypertension. Meanwhile, observed the change of above|mentioned marker after losartan therapy.Results:CD63?CD62P concentration in EH were significantly higher than those of the normal subjects(P005 or P001);There were positive correlation among CD63?CD62P and hypertension stage?stratification of risk; platelet CD63?CD62P concentration decreased after 8 weeks losartan therapy(P005 ~001).Conclusion:There were positive correlation among CD63?CD62P and the hypertension stage?stratification of risk,CD63?CD62P may predict prognosis of EH.Losartan can decrease blood pressure and ameliorate the abnormality of platelet activation at same time." @default.
- W2384877417 created "2016-06-24" @default.
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- W2384877417 date "2001-01-01" @default.
- W2384877417 modified "2023-09-23" @default.
- W2384877417 title "The changes of platelet CD63、CD62P levels and effects of angiotensinII type 1 receptor antagonism on them in essential hypertension" @default.
- W2384877417 hasPublicationYear "2001" @default.
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