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- W2384885708 abstract "Objective: To investigate the clinical significance of miR-221 in plasma from patients with colorectal cancer(CRC).Methods: The plasma levels of miR-221 from 60 healthy controls and 80 patients with CRC were measured by real-time reverse transcription-polymerase chain reaction(real time-PCR).Results: 1.The plasma levels of miR-221 were markedly higher in CRC group than in controls group,which showed increasing trends with the development of the duke stage.2.Patients were in line with surgical treatment conditions and the plasma levels of miR-221 were detected in the seventh day after surgical treatment.There was a significant difference between patients before treatment and after treatment.3.The CRC patients were grouped by the relative plasma levels of miR-221,the incidence of cancer recurrence was higher in group with high plasma levels of miR-221 than that in group with lower level within 2 years after surgery.Conclusion: The plasma levels of miR-221 are helpful to diagnose CRC and judge the progression and prognosis of the disease." @default.
- W2384885708 created "2016-06-24" @default.
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- W2384885708 date "2012-01-01" @default.
- W2384885708 modified "2023-10-08" @default.
- W2384885708 title "Clinical significance of miR-221 in plasm from patients with colorectal cancer" @default.
- W2384885708 hasPublicationYear "2012" @default.
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