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- W2384910588 abstract "Objective To investigate the correlation between the levels of serum Brain Natriuretic Peptide(BNP) and primary hypertension(EH) complicated with left ventricular hypertrophy(LVH),and to observe the effect of amlodipine on the levels of BNP.Methods 120 patients with light or moderate hypertension were selected,40 healthy subjects served as control group.The hypertensive patients were given amlodipine for 6 months,then the levels of BNP,systolic blood pressure(SBP),diastolic blood pressure(DBP) and index of LVMI were detected.Results before treatment the levels of BNP SBP,DBP and LVMI in LVH group and the NLVH group were significantly higher than those in control group(P0.01).After treatment with amlodipine,the levels of BNP,SBP,DBP and LVMI in LVH group were significantly higher than those in LVH group(P0.01).The levels of BNP and LVMI decreased slightly in NLVH group after treatment with amlodipine,however,the difference was not significant(P0.05).There was a positive correlation between BNP and LVMI(r=0.43,P0.01).Conclusion After treatment with amlodipine,the levels of BNP and LVMI in LVH group are significantly higher than those in control group.There is a positive correlation between the levels of BNP and LVMI.The amlodipine can not only decrease blood pressure but also can reverse EH complicated with LVH." @default.
- W2384910588 created "2016-06-24" @default.
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- W2384910588 date "2009-01-01" @default.
- W2384910588 modified "2023-09-23" @default.
- W2384910588 title "Effect of serum BNP on primary hypertension complicated with left ventricular hypertrophy" @default.
- W2384910588 hasPublicationYear "2009" @default.
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