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- W2384936827 abstract "Objective To study the relationship between pS2 protein expression and adjuvant endocrine therapentic effect in breast cancer.Methods Applying immunohistochemical technique(S P),we detected the expression of pS2 protein in 100 primary breast cancer specimens,and the prognostic data were analyzed in combination with the correlation of menopausal status,lymph node status,adjuvant Tamoxifen therapy respectively.Results The positive rate of pS2 protein was 57%.In the 64 cases of premenopausal whose pS2 protein was positive expression,and with adjuvant Tamoxifen therapy,the five year survival rate was higher than those who had not such therapy( P 0.05);In the 56 cases of patients with lymph node metastasis,when pS2 protein was positive expression,the five year survival rate was higher in these who had administered tamoxifen( P 0.05);In the patients who had administered adjuvant Tamoxifen therapy,long rank test indicated that the overall survival rate was higher in patients with pS2 positive expression than those with ER positive expression( P 0.05).Conclusion pS2 protein appears to be a factor that can be used to instruct the endocrine therapy of breast cancer." @default.
- W2384936827 created "2016-06-24" @default.
- W2384936827 creator A5046454314 @default.
- W2384936827 date "2002-01-01" @default.
- W2384936827 modified "2023-09-25" @default.
- W2384936827 title "Study on the Relationship Between pS2 Protein Expression and Adjuvant Endocrine Therapeutic Effect in Breast Cancer" @default.
- W2384936827 hasPublicationYear "2002" @default.
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