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- W2384978048 abstract "Electrophysiological method was used to study the pre and postsynaptic receptors in the tectum of adult Xenopus frogs. Whole cell voltage clamp recording of neurons in the sixth layer of optic tectum of slices revealed the higher frequency of spontaneous miniature inhibitory postsynaptic currents (mIPSC) than that of spontaneous miniature excitatory postsynaptic currents (mEPSC). Carbachol and other nicotinic receptor agonists (cytisine and nicotine) induced marked increases in the frequency of both spontaneous miniature postsynaptic currents (mPSC) in the presence of tetrodotoxin (TTX) and atropine, whereas they had no effect on amplitude. The nicotinic acetylcholine receptor (nAChR) competitive antagonist, dihydro β erythroidine (DH β E), blocked the carbachol induced enhancement of mPSC. Mecamylamine, a nAChR selective antagonist, failed to block all, but a few neurons enhancing frequency of mPSC." @default.
- W2384978048 created "2016-06-24" @default.
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- W2384978048 date "2001-01-01" @default.
- W2384978048 modified "2023-09-25" @default.
- W2384978048 title "Modulation of presynaptic nAChR on mPSC of optic tectum in adult Xenopus frogs" @default.
- W2384978048 hasPublicationYear "2001" @default.
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